Abstract: In view of the notice issued by the State Administration of Coal Mine Safety Supervision on the acceptance specifications for the Upgrading and Transformation of Coal Mine Safety Supervision and Control Systems, as well as the requirements of AQ 6201-2019 on technical indexes such as digitalization, anti-electromagnetic interference, inspection cycle, remote control, etc., a low-power all digital optical interface substation based on multi-bus architecture is designed. The substation has RS485, CAN, optical interface and other bus structures, and the key technology of man-computer interaction for reducing power consumption in substation are discussed, through the independent design of the traditional human-computer interaction display function, the power consumption is reduced obviously. Through various tests submitted by the system for inspection, all indexes of the sub-station are higher than the standard requirements, and the electrical fast pulse group immunity test of system has reached level 3 A, and the surge level 4 B, with high electromagnetic compatibility level, stable and low power consumption and other characteristics.