Abstract: In order to further accelerate pressure relief drainage, for the gas area management work needs of low permeability and strong adsorbed coal seam, through a large number of laboratory simulation and analysis, we studied the laws of gas desorption under different adsorption equilibrium state of coal seam in Zhongma village. The results show that the higher the equilibrium pressure of the same coal sample, the more the adsorption quantity of gas, the faster the desorption rate and the more the unit time of desorption quantity in the same time period; to speed up the gas desorption of coal seam needs some space for unloading pressure to shorten the passage of gas migration; the larger the coal sample size is, the more free gas in the pore fissure, the more disadvantageous to release.