Abstract: In order to solve the surrounding rock control and roof support problems in Zhaolou Mine which are under one thousand meters deep, the integrated approaches of FLAC^3D numerical simulation, the key layers theoretical calculations and field measurement are used to study the laws of mine pressure activities in the first mining area of Zhaolou Mine. The study obtains the parameters including key layer horizon, the first weighting interval and periodic weighting interval and so on, which plays a guiding role in safety production of working face.