Abstract: Safety discipline was a frontier science and interdisciplinary. The interdisciplinary characteristic determined its diversity of research methods in the field of scientific research. As one part of it, coal mine safety issue was the great subject which affected and restricted safe and high efficiency development of the coal industry. Mastering the research methods of coal mine safety discipline effectively, which was the necessary condition of carrying out research actively, deepening the theory understanding and enhancing the level of technical equipment of the industry. It took safety discipline (mining engineering) development achievements of Henan Polytechnic University as main line. Combined with the actual background of industry production, it studied the research methods of coal mine safety discipline.