Abstract: In order to study the effect of surfactant compound on droplet size characteristics in fog field, an experimental platform was independently built in this paper. Anionic surfactant AES, amphoteric surfactant LAB-35 and non-ionic surfactant AEO-9 were selected for binary monomer re-combination, and different ratios of surfactant compound solution were used for experiments. The droplet sizes D₁₀　, D₅₀　, D₉₀　, Dv and Δs were analyzed under different pressures. The results show that when the nozzle diameter is constant, the droplet size of surfactant compound solution decreases with the increase of spray pressure, and the droplet size distribution is more uniform with the increase of spray pressure. In the range of 5∶1-1∶5 ratio of AES and AEO-9 compound solution, the spray droplet particle size is smaller than that of AES and AEO-9 monomer solution. AES and LAB-35, AEO-9 and LAB-35 compounds are all easy to reduce the spray droplet size of LAB-35 monomer solution.