Abstract: In order to realize the intelligent decision-making of the pipe diameter optimization scheme of the mine gas extraction pipe network, the gas extraction pipe network diagram theory model is constructed based on the principle of graph theory, and the specific pipe diameter pipe network is solved based on the gas-air hybrid flow model of the pipe network. Taking the minimum pipe network investment as the target function and the pipe diameter as the decision-making variable, the pipe diameter optimization model of the gas extraction pipe network is established. Based on the genetic algorithm of integer coding, the pipe diameter optimization scheme of the extraction area on the west side of Liuzhuang Coal Mine was obtained. The results show that the combination of pipe diameter optimized by genetic algorithm is better than the flow rate method in terms of economy and extraction effect, and the negative pressure of extraction at the extractive end after optimization meets the extraction requirements, and the cost of pipe network is reduced by 483,000 yuan.