Abstract: Taking the complex fault zone of group A coal mining in 12123 working face of Pan’er Mine in Huainan Mining area as the research object, a micro-seismic monitoring system was established to obtain the micro-seismic activity data in the structural development area, and the distribution of micro-seismic events and the response characteristics of source parameters during the deterioration of rock mass in the fault zone were analyzed, revealing the mechanical mechanism of the induced micro-seismic response. The results show that micro-seismic events show significant spatial and temporal characteristics with the relationship between mining and faults. The cumulative energy, b value, energy index and cumulative apparent volume change gradually with mining, which can effectively reflect the failure state of fault surrounding rock. Under the influence of “triangular isolated island area” of rock mass formed by mining line and structural plane, the energy released by rock mass failure induced by regional concentrated distribution of stress shows a space-time migration characteristic.