Abstract: Surfactant, as one of the effective methods to improve the wettability of dustproof water, was widely used in dust control work of coal mine. Through surface contact angle and surface tension experiment of different surfactants and complex ligand reagent under the same condition, the wettability was separately analyzed, and the conclusion that complex ligand reagent B, BS-12, penetrating agent T, APG had a better wettability was reached, moreover, the wettability was closely related to the physical and chemical properties of the surfactant monomers.