Abstract: In recent years, as coal mining strategy has moved westward in China, rockburst has now become the most severely affected coal mine disaster in Ordoes area. This paper takes Hongqingliang Coal Mine in Tarangole Mining Area of Ordos coalfield as the background, and conducts a systematic study on the prevention and control of rockburst under the conditions of deep mining in Tarangole Mining Area. The research shows that the deep mining in Tarangole Mining Area is under the geological conditions of “weak cemented overburden + high strength coal”. The deep mining rock burst in Tarangole Mining Area is caused by the accumulation of a large amount of elastic energy in the hard coal body due to high-intensity mining. The prevention and control strategy of rock burst combining reducing coal strength, controlling pushing speed, optimizing section coal pillar size, and strengthening support was proposed. Hongqingliang Coal Mine adopts comprehensive measures such as drilling pressure relief, control of mining speed, and strengthening of mining roadway support. The on-site microseismic monitoring data confirmed the effectiveness of the prevention and control of rock burst and realized safe and efficient mining of the mine.