Abstract: In order to obtain the migration law of coal dust and spray droplets under the action of air current, the geometric model of coal mine roadway and major equipment is established based on the actual situation of a coal mine fully mechanized excavation face. The DPM model of the FLUENT software is used to carry out the coupling numerical simulation of air flow, coal dust and spray droplets in the fully mechanized excavation face. According to the numerical simulation results, the wet dust removal method combined with the wall-attached air duct under the condition of long pressure and short ventilation has achieved remarkable dust removal effect, and the air curtain formed by the radial air flow from the wall-attached duct has effectively inhibited the movement of coal dust toward the back of the tunnel. Through the analysis of transient results, we clearly know the migration trend of coal dust and spray droplets. Dust and spray droplets in general have been gradually spread to rear of roadway and gradually caught in the area between the machine and the cutting surface, also found that coal dust and spray droplets gradually reduce within 30 seconds, particle concentration in machine driver sharply increased first, and then gradually reduced.