Abstract: Based on the data of the two water releasing tests and “5.25” water inrush of collapse columns of Pan’er Coal Mine in Huainan Coalfield, the hydraulic connection between the main aquifers and transmissivity-impermeability of faults were systematically analyzed by means of groundwater system analysis, structural water control theory and statistical analysis. The results show that: there a close hydraulic connection between Ordovician limestone aquifers with C3III group limestone aquifers of Taiyuan Formation with the same water level response and variation range. Besides, the hydraulic connection between Ordovician limestone aquifer with C3I and C3II group limestone aquifer of Taiyuan Formation is weak. F1 fault is impermeability in C3I and C3II group limestone aquifer of Taiyuan Formation but transmissivity in C3III group limestone aquifers of Taiyuan Formation and Ordovician limestone aquifers. In addition, DF1 fault is impermeability in C3I group limestone aquifer of Taiyuan Formation but transmissivity in C3II, C3III group limestone aquifers of Taiyuan Formation and Ordovician limestone aquifers.