Abstract: To study the waterproof coal pillar design for mining in the outcrop area of thick coal seam in Shanxi Formation under the large Jurassic red stratum in the seventh mining area planned and designed by Dongtan Coal Mine, the systematic analysis is carried out on six boring-enclosed areas near the typical outcrop area, and the Jurassic thickness and the interval contour line between the top plate of the third upper coal seam and the bottom of the Jurassic red stratum are drawn. On this basis, the engineering geological profile of typical third upper coal seam mining is established, and the typical borehole is taken as the case to discuss the waterproof coal pillar design for thick coal seam mining under thick red stratum by using the analogy analysis and related specification.