Abstract: Based on Open CASCADE and Ordinary Kriging interpolation algorithm, a software development framework adding geostatistical interpolation algorithm to CAD geometry operation core for three-dimensional hydrogeological modeling is designed. Using three-dimensional graphics rendering of Open CASCADE, visual interaction, editing functions and geo-statistics interpolation function of Ordinary Kriging, we designed the hydrogeology modeling software for mine by taking Visual Studio as development tool, C++ and Python as development language, and SQLite as geological database, developed and Hydrogeo3D mine hydrogeology modeling software to realize the editable function of local details in the modeling process.