Abstract: The application of stress-dominated precise outburst prevention and control technology was researched with the engineering background of 11501 working face of 11-2 coal seam in Zhujixi Coal Mine, a kilometer deep mine. Gas mechanics parameters of coal seam and its roof thick and hard rock are tested, the risk of coal seam outburst and the impact tendency of coal seam are evaluated, the attributes of mining dynamic disasters in 11501 working face were analyzed, the method of dynamic hazard zoning was studied and regional prediction was made, the regional pressure relief measures of large diameter borehole, roof deep hole pre-splitting blasting, water injection in coal seam and outburst prevention measures in pre-drainage area along borehole were formulated, gas emission control technology of mining adjacent strata in working face was matched. The effects of dynamic hazard prevention and control and gas control were investigated. The results show that: the maximum predicted cuttings amount was 3.9 kg/m, the maximum residual gas content was 5.14 m³/t and the gas concentration of return air flow was below 0.45% during mining period with no accidents of exceeding forecast indexes and gas limit occurred, accurate prevention and control of stress-dominated outburst dynamic disaster zoning and grading has been realized.