Abstract: To solve the problem of inverted air airflow in main inclined shaft in winter, the causes and process of natural wind pressure reverses airflow in roadway were analyzed. Three air flow reverse control schemes for main inclined shaft were proposed based on theoretical analysis. Three-dimensional mine ventilation simulation model is established on the basis of reasonable simplification of the ventilation system in Guojiahe Coal Mine. Three control schemes are simulated by network air distribution on the basis of three-dimensional mine ventilation model. Improvement of air flow temperature in auxiliary inclined shaft has been optimized. The simulation results show that increasing the air flow temperature in the secondary inclined shaft can solve the problem inverted air flow in main inclined shaft in winter. At the same time, it can reduce the natural air pressure and mine ventilation resistance between the main and auxiliary inclined shaft. Increasing the power of the ground heater can maintain the air flow temperature in the secondary inclined shaft when the ground temperature continues to decrease in winter. It can prevent inverted air flow in main inclined shaft and ensure the stability of ventilation system.