Abstract: With the increase of mining depth, heat damage, dust, noise, toxic and harmful gases are listed as four major occupational hazards in coal mines. Studying the occupational hazard prevention and control system of high ground temperature mines is of great significance to protect the safety and health of miners. Based on the actual situation of Longgu Mine, a comprehensive prevention and control concept of mine occupational hazard in high ground temperature environment was proposed. An occupational hazard prevention and control technology system and an occupational hazard prevention and control management system were built to protect the health of miners. This paper has important implications for the prevention and control of occupational hazards in mines.