Abstract: To analyze the failure law of overburden strata in multiple seams mining, the 8601 working face of Ansheng Coal Mine and the 8501 working face of 5^# coal were taken as the engineering background. The theoretical method was used to calculate the height of the fracturing water in the single coal seam of 8501 working face, and FLAC^3D software was used to simulate overburden failure laws and water-conducting development characteristics of multiple seams mining. The result shows that the theoretical height of the water-conducted zone is 65.35 meters, accounting for 84.87% of the layer spacing; under multiple seams mining conditions, the distance from 8501 working face is 200 meters. The low stress region is generated, and the vertical stress peak is about 6.2 MPa, which is 32.6% lower than that of single mining. This area has a large area of plastic damage, with a layer spacing of 77 meters. Overburden rock produces long enough channel to cause water damage. Engineering practice shows that 8501 working surface has been safely completed without water damage after the drainage of the old empty area.