Abstract: To effectively curb the serious impact of coal mining water inrush disasters on mine safety production, seeking the intrinsic mechanism of inducing water inrush from coal mines and the law of micro-cracking, and then analyzing and predicting coal mining water inrush disasters, microseismic monitoring technology was combined with the hydrogeological conditions of Dongjiahe Coal Mine to establish a microseismic monitoring system. Microseismic monitoring was performed on the floor of 22517 working face in Dongjiahe Coal Mine, and a method of determining the floor destruction depth through microseismic monitoring and columnar comprehensive analysis of geological drilling was obtained. Microseismic monitoring results show that the microseismic events are mainly distributed in three regions. The overall trend of the floor of the 22517 working face of Dongjiahe Coal Mine is stable, but the local damage may occur, so that the permeability coefficient of the local rock mass is increased to form the floor water outlet point, which may be located between 50 m in front and 30 m behind the working face.