Abstract: Aiming at strong mining earthquakes during excavation process of the gob-side roadway with hard roof in Xuzhuang Coal Mine, by the theoretical analysis and seismicity monitoring, the time and spatial location of the strong mining earthquakes were determined, and hard roof, excavation disturbance, fault structures and the coal-seam variation are the sources of disasters caused by impact during roadway excavation. According to the geological and mining technology conditions, comprehensive prevention measures of roof blasting, drilling relief and reducing excavation speed are proposed, the seismicity monitoring results showed that these measures effectively reduced the frequency of strong mining earthquakes. And the impact failure degree is reduced to guarantee the safety of roadway. The practical application proves that the comprehensive prevention measures can effectively prevent the rock burst during excavation process of the roadway with hard roof.