Abstract: To compare the effects of cement, gypsum and humic acid on the material strength and gas desorption of coal and gas outburst similar materials. Uniaxial compressive strength and initial velocity of gas emission of similar materials under different binder conditions were obtained by using rock triaxial testing machine and gas emission initial velocity tester. The results show that the uniaxial compressive strength of similar materials increases with the increase of the proportion of binder, and taking cement as binder has the largest influence on the uniaxial compressive strength of materials. With the addition of 20% cement, gypsum and humic acid, the maximum uniaxial compressive strength of the material was 6.165, 2.02 and 1.63 MPa, respectively. The initial gas release velocity of the material decreases with the increase of the binder proportion, and the initial gas release velocity of the material changes from large to small, followed by cement, humic acid and gypsum.