Abstract: The coalbed methane resources of Guizhou Province are abundant, mainly concentrated in the western Guizhou region. According to the results of gas logging in the western Guizhou region, it is found that the shale formation between coal seams has good gas measurement and has the value of development and utilization. Through the study gas content properties and the pressure coefficient features of coal measures strata in the western Guizhou region, this paper analyzes the “five-stage three-pressure method” drainage and mining technology of coalbed gas well and the “three-stage” drainage and mining control of shale gas well, summarizes the drainage difference of CBM and shale gas well, and proposes drainage control scheme of co-mining the CBM and shale gas.