Abstract: According to the difficulty problems of deformation and destruction of the main rail-tunnel with weak surrounding rock and complex geologic structure at Xinzhi Coal Mine, and the reasons for the deformation and destruction and the laws of mine pressure behavior for this main rail-tunnel are analyzed, and the combined support scheme “bolt-grouting and anchor network cable spray” is adopted after combined with the theoretical analysis and the test of practice. According to field industrial test, during the period of observation, cumulative convergence deformation of two sides is about 33 mm in rail tunnel, roof and floor cumulative deformation rate is approximately 28 mm, the phenomena of two sides convergence of roadway, roof subsidence and floor heave are gentle, that is, the effect of the optimized design scheme is obvious.