Abstract: This paper summarizes the effect of different height characteristics on the escape speed of miners under different water level in the period of mine water flood and analyzes the functional relationship between the walking speed and water level of miners with different height at different water level, proposes and sets up the corresponding relation function model which is the mathematical model of retarding speed curve in water, and calculates the influence coefficient of miners’ escape velocity based on this model. In order to describe the safety capacity of roadway dynamically, according to the fuzzy evaluation principle, the corresponding safety factor is introduced. Finally, combining with the actual roadway characteristics, the mathematical model of mine flood escape is optimized. Then, the optimized mathematical model can not only design the optimal escape route for miners with different height characteristics, but also design the optimal escape route with average height when there are more staff.