Abstract: With the opening and extending to the West and production needs of mine,the needed wind roadways in 33^# mining area of Xin’an coal industry company of Shandong Enery Zaozhuang Mining Group are increased,which makes the ventilation network complexity.Affected by natural wind pressure and mine resistance and other factors,roadway is prone to appear the breeze,no wind,or even inverted air current phenomenon which caused by unstable air current.According to production layout and mining connection in 32^# and 33^# mining area,fully considering the needs of mining ventilation,through analyzing,demonstrating and reasonably adjusting and optimizing mine ventilation system,the goals of achieving intrinsic safety of mine ventilation system by safety,high efficiency and reasonable production are realized.