Abstract: By establishing a safety management information system, coal enterprises can realize rapid feedback, dynamic tracking and closed-loop control of safety information at production sites, automatic assessment and evaluation of safety management, and sorting and analysis of safety information from different information sources to achieve safety. Based on the investigation of the safety management status of Shendong Coal Group Corporation, combining the background and purpose of system development, taking the implementation characteristics and key elements of the system as the key points, and taking the application analysis and management of the system as the lines, the application and practice of the system is studied comprehensively. On this basis, through the application of the system, the actual role of the system in the safety management is verified, and the difficulties in the implementation and application of the system, the corresponding suggestions and countermeasures are proposed, so as to promote the enterprise’s attention to the system and more prospects and input. And explore the application mode of safety management information system in coal mines, and serve as a reference and guide for the popularization and application of system applications in the coal mining industry.