Abstract: The control techniques for Ordovician limestone karst water disaster with high-pressure in deep mining is proposed in this paper to solve the problem of Ordovician limestone karst water disaster in Fengfeng Mining District. By using directional horizontal well group technology, grouting reinforcement is carried out for the weak zone and hydrological anomaly area of coal seam floor to block the potential channel and enhance the integrity of the floor. At the same time, a certain range of rock strata in the top part of the Ordovician limestone has been converted to a relative aquifer, and the application point of the aquifer is moved down, which increases the thickness of the effective waterproof layer and can liberate a large number of raw coal resources. The application in large mining deep well of Fengfeng Coal Mine shows that this technique prevents the ash water disaster accidents and ensures the mine safety production.