Abstract: According to the low oxygen phenomenon occurred at 22102 fully-mechanized coal mining face in Shangwan Mine during the mining process, we study the causes of low oxygen and propose the application of pressure balancing ventilation to solve this problem, and carry out field measurement. According to the monitoring results, we optimize ventilation parameters. At the same time, by taking integrated control technique measures such as installing air resisting curtain and air guiding curtain, sealing air leakage of mined out areas and strengthening monitoring and control, the oxygen concentration is at normal level and safe and efficient production of mine is guaranteed.