Abstract: Based on the Weibull equation of desorption, from the perspective of analytical efficiency, a new formula for calculating sensitive pressure, transition pressure and transition pressure is given, and the process of desorption is divided into five stages by combining the critical pressure. Based on the actual isothermal desorption experiment data of No.3 coal, the differences between Weibull isotherm equation and Langmuir isothermal equation were analyzed. When the temperature is high, the Weibull isothermal solution equation is more consistent with the experimental data. The influence of temperature on the efficiency and key pressure is analyzed; to achieve the same desorption efficiency, the higher the temperature, the lower the required pressure; the key pressure increases and then decreases with the increase of temperature; in the same initial pressure of the formation, during the process of isothermal desorption, the higher the temperature, the less pressure to end the desorption, the more pressure range of the desorption; when the initial pressure of coal seam and the content of coal bed gas are certain, the higher the temperature, the more the desorbing gas content.