Abstract: To study the mining-induced mechanical characteristics influence on the permeability of coal, seepage experiment and theoretical analysis are adopted. The permeability experiments of two groups of coal samples from two mines are implemented to reveal the permeability variation regularity under two mining stress distribution. The results are shown as follows: the curve of permeability has the similar change under two mining stress distribution, but the characteristics of permeability are different under the different phases of paths；in the process of quasi-hydrostatic pressure, the permeability under two mining stress distribution decreases with the increasing of initial axial force. On the whole, the permeability under protective coal mining stress distribution is higher than that under top-coal mining stress distribution. In the second loading and unloading phase, the permeability shows a slow upward trend under top-coal mining stress distribution, the unloading confining pressure plays a dominant role on the change of permeability coefficient of coal, but the permeability under protective coal mining stress distribution begins to increase at the end of loading and unloading process；the coal permeability distribution can be divided into slow increase stage, growth stage and rapid increase stage in the forward process of working face. The effect of gas drainage is more ideal, especially after the peak stress points near the working face.