Abstract: Based on the micro-seismic monitoring data during the mining of a mine 3307 working face, we statistically analyzed the source energy and vibration frequency of micro-seismic events and dynamically predicted strong mine earthquake events with shock wave CT technology. Research results show that: by using shock wave CT technology, we calculated the wave velocity anomaly coefficient An and wave velocity gradient coefficient of variation VG contour map of coal seam, roof and floor, and determined high wave velocity positive anomaly and wave velocity gradient anomaly regions, spatially marked off strong dangerous area of rock-burst; by analyzing the time distribution table of micro-seismic events, we explored the coupling laws of daily total energy and frequency of micro-seismic and strong mine earthquake events, temporally determined the dangerous period of rock-burst by combining with An and VG contour map; compared with the field test data, the validity of the forecast results is verified in space and time.