Abstract: According to the occupational health monitoring results of coal mine and technical specifications of occupational health monitoring, in order to evaluate status of coal mine occupational disease hazards, we select industrial dust, SO₂, NO₂, CO, noise and temperature as evaluation factors. Through the establishment of membership function and the weights sets of various hazards, we use fuzzy comprehensive evaluation to carry out occupational disease evaluation for coal face, coal roadway tunneling face, shotcrete supporting point, electromechanical chamber excavation drilling working face of coal mines in Guizhou province. The results show that the occupational hazard factor in Guizhou province is industrial dust. The order of occupational hazards evaluation results from good to bad is electromechanical chamber, excavation drilling working face, coal roadway tunneling working face, coal face, shotcrete support point.