Abstract: In view of the problem that it is difficult to generalize boundary conditions and internal structure of Ordovician limestone aquifer in the numerical prediction of mine discharge, taking Danhou Mine of Yuxian Mining Area as an example, we established regional natural boundary model, depicted the hydraulic nature of boundary conditions and heterogeneity of internal structure of Ordovician limestone aquifer based on the analysis of many data, such as pumping test, geological section and water inrush. Finally, on the basis of using underground water level dynamic observation data to identify and verify model, we forecasted water discharge under the way of drainage mining.