Abstract: In order to simulate real ventilation system accurately, we summarized and analyzed ventilation analogue simulation software, and integrated AutoCAD software with mine geographic information system by using combined technology of GIS, AutoCAD. Based on unified data source of spatial database or graphics, we realized synchronous application and display of two and three dimensional roadway graphs, and achieved interoperability of data and graphics. All this can effectively achieve roadway cut-through simulation, airtight simulation, anti-wind exercise simulation, mine main fans selection, ventilation optimization, and guarantee stability and reliability of ventilation system.