Abstract: In view of the prevention and control of coal and gas outburst of 15^# coal seam in Sijiazhuang Coal Mine, we analyzed the stress releasing laws and inflation deformation effect of protected seam under the condition of upper protective seam mining and underside bauxite protective seam mining, evaluated the feasibility of conducting upper protective seam mining and underside bauxite protective seam mining in Sijiazhuang Coal Mine, proposed the optimal scheme of regional outburst prevention using protective seam mining. Research results show that the pressure relief inflation effect of upper protective seam is not enough to completely eliminate the outburst danger of 15^# coal seam; the bauxite under 15^# coal seam has certain mining economic value, the protected seam can get sufficient pressure relief after the underside protective layer mining, the protected 15^# coal seam gas can get effective drainage, thereby eliminating the outburst danger; the technical scheme of regional outburst prevention in Sijiazhuang Coal Mine using underside bauxite protective seam mining is more appropriate, but its mining height cannot be more than 4.8 m, and pressure relief gas of 15^# coal seam must be extracted.