Abstract: REG k-ε turbulence model of Fluent software was used to carry out numerical simulation for local wind resistance of mine automatic control wind window which was installed in Wangpo Coal Mine ventilation-connection laneway 3205 coalface. The results of numerical simulation show that with the increasing of opening-area of wind window, the local wind resistance of wind window decreased in negative power function form, and with increasing of ventilation rate, it decreased in negative exponent form function form. According to the results, the calculation formula of the local wind resistance was obtained from opening-area of wind window and ventilation rate. The local wind resistance was measured and the best formula was determined. Compared with the measured results, the error of the results from the best formulas was less than 8 percent.