Abstract: To make the occupational health management has an outstanding main point and specific aim, on the basis of analyzing occupational hazard factors of different sites in coal mine and fuzzy clustering analysis method, the evaluation index system was established and quantified; after a series of matrix calculation, different operating sites with occupational hazard factors were clustered, the similar relationship among different operating sites was got. After application, the result showed that the degree of occupational hazard of mining working face and driving working face was the most serious, which should be paid more attention; the degree of occupational hazard of working section sub-station and distribution cavern was relatively serious, which should be paid attention; the degree of occupational hazard of other working site was serious, which should not be ignored.