Abstract: Taking GP-6 shaft in Guizhou Songhe Mine as research object, based on the drainage production data after staged fracturing, we evaluate multiple seam staged fracturing effect in this area. The results showed that selecting reasonable perforation fracturing layer and using the staged fracturing technique can effectively improve the gas production potential of the coal reservoir and improve the gas production capacity of the coalbed methane well for the coalbed methane development in multiple seam of Guizhou Songhe Mine according to the geological data, drilling data and related test analysis data. Staged fracturing technology in multiple seam of coalbed methane development has obtained good effect in Guizhou Songhe Mine.