Abstract: In this paper, the developing of plastic zone, the change of pore pressure in the fissure zone and the change of seepage quantity were used as criterion to study water inrush risk of hidden Karst collapse pillar with mining disturbance. By stress-fluid coupling formula and FLAC^3D software, the water inrush process of hidden Karst collapse column under the impact of mining disturbance and hidden depth was numerically simulated. The results showed that plastic zone developed in the form of shear failure from the bottom of hidden collapse pillar with mining disturbance, when the plastic zone near hidden Karst collapse pillar connected with the plastic zone near working face, the groundwater inrush occurred. The impact of mining disturbance is much more in the hidden Karst collapse pillar with thinner hidden depth. When the thickness of hidden depth is less than 30 meters, there is a greater possibility of water inrush in actual project.