Abstract: As a large-scale coal mine enterprise, subordinate mines are more; often using multilevel management mode will inevitably cause the difficult control of safety and frequent safety accidents. In this paper, the research on the rapid response of the "safety information" for the mine safety information is based on the classification of the mine safety anomaly information. A series of fast response mechanism of mine safety information is developed to adapt to the multilevel management mode, which has played a good effect on safe production management to reduce or prevent major accidents.