Abstract: In order to solve the prediction problems of coal and gas outburst in Wangjiazai Mine, the coal and gas outburst real-time tracking and early warning system is applied, and the each change trend between microseismic signals (big event, small event, energy) and gas parameters in the same time and space during P41104 heading face passing through fault, coal pillar area, the scope of the protective layer is analyzed, and the hazard level is concluded. According to the results of warning, appropriate outburst prevention measures and excavation process are used, which greatly improves mine safety and production efficiency.