Abstract: According to comparison and analysis of the control techniques about Ordovician limestone karst water disaster and status quo of mine water control in Fengfeng Group, regional advanced governance technology in combination with time and space have been proposed to solve the problem of Ordovician limestone karst water disaster. The regional advanced governance technology detected and grouted the fissures in coal seam floor water-resisting layer by the ground level multi-branch drilling technology; hydraulic connection between Ordovician limestone aquifer and upper aquifer was cut off, and then raised the bottom water-blocking ability.