Abstract: According to current situation of ventilation system of Yuwu Mine, selecting two main test routes, the ventilation resistance of mine ventilation system was determined, the measured ventilation parameters were obtained and verified through ventilation network solution, the operation status of mine ventilation system was grasped; the current existing issues were identified. And the feasible optimization scheme was proposed combining with mining deployment and air volume demand distribution, which provides strong support for the improvement of mine ventilation management level and economic efficiency.