Abstract: In order to solve the problem of waste filling pipe wear, the article, based on the actual situation of filling pipeline wear, designed a series of pipe wear method to analyze the material of wall, velocity of slurry and slurry in pipe corrosion, diameter of slurry. In the end, we found that when we control a single variable, the decrement of quality about diameter, corrosion, material, and velocity is 213 g, 161 g, 145 g, 61 g, and concluded the roughly sorted of different factors influencing pipe wear, which can provide the theoretical basis for reducing the wear of the pipeline.