Abstract: In order to properly analyze the impact of mining on surface and railway lines, according to geological and mining characteristics of a mine working face, the FLAC^3D software is utilized to establish the numerical model, the rock mechanics parameters of the model are obtained based on displacement back analysis method combined with orthogonal and uniform design. Simultaneously, the obtained model parameters are applied to predict the influence of mining above the nearby working face on railway line. The results show that the resulting surface subsidence inversion parameter can better meet the actual situation; through the comparative analysis of subsidence range between predicted and measured results of the railway line, the dynamic prediction result of sinking length of the railway line meets the basic accuracy needs, which confirms the reliability of the model and the selected parameter in this study.