Abstract: Taking the No.42104 fully mechanized caving face in Buertai Coal Mine of Shendong Coal Group as the example, the spontaneous combustion of residual coal is easy in goaf, and the reason is analyzed. Combined with the actual production conditions of the working face, insisting on the principle "prevention first, comprehensive treatment", comprehensive control measures are proposed, such as strengthening the observations of the gas in three-zone of goaf, optimizing the nitrogen injection method of goaf, selecting the best grouting materials, determining the key zone of grouting, and sealing the channels of air leaking.