Abstract: Coal mine ventilation system is one of the important systems in coal mining process,and it has special significance to discuss and analyze its safety and stability.When the airflow of ventilation system is unstable,it will seriously affect the air volume supply of the working place,which will cause the occurrence of gas accidents.This paper discussed the safety and stability issues in the coal mine ventilation system,and analyzed the characteristics of the ventilation system.The influence degree and range of two major factors were discussed.Therefore,maintaining the safety and stability of coal mine ventilation system is fundamental for safety production.