Abstract: Through the analysis of microseismic monitoring system in Hujiahe Coal Mine, we study the time and space distribution law of mine earthquake for tunneling roadway in folded region, analyze the typical characteristics, and propose control means. Results show that the mine earthquake occurred in folded region is induced by both tectonic stress and mining influence, and microseism events are mainly concentrated in the A4 anticline in the range of 180 m; the high-energy microseism events burst quickly when it release its energy and its vibration wave velocity will be changed from a low level to a high level; microseism events can be controlled by reducing tunneling speed and weakening the strength coal and rock.