Abstract: Aiming at the cause and area of easy spontaneous combustion in Qianqiu Mine 21141 fully mechanized caving face during stop production, close and unsealed period, the main fire prevention measures are adopted as follow. Firstly, during stop production period, reducing the air volume and closing the upper and lower corner by grouting and diffuse stents and filling to reduce leak wind. Secondly, during the face closed, nitrogen injection and pressure balance ventilation in closed area are used. Thirdly, air lock unsealed method are used. In addition, comprehensive fire prevention technologies such as all-round fire drill, filling gel, cement, three-phase foam and other technologies are also adopted, which achieves the goals that the working face unsealed safely and successful production.