Abstract: Taking a typical deep mine with high risk of rock-burst as background, the stress state of "roof-seam" structure body was analyzed, and a rock-burst prevention technology system is established based on stability of "roof-seam" structure body and taking stress control as the center. According to the numerical simulation and theoretical analysis, the relevant parameters which include width of section coal pillar, size and layout of roadway and some technology methods of regional stress coordination and local stress control such as coal blasting for pressure relief and big borehole for pressure relief were designed and optimized. The study shows that width of section coal pillar which is from 3 to 4 m has a good effect on prevention for rock-burst, the roadway layout with big size along roof can prevent the occurrence of rock-burst better. However, the effect of rock-burst prevention by stress control will not change with the increase of size of roadway. Some parameters including depth of blasting holes and length of sealing have to make a dynamic adjustment. When the depth of hole is 30 m, diameter of hole is 130 mm, space of hole is 1.2 m, the stress control is obvious.