Abstract: The paper ananlyzed unreasonable problem of ventilation regulation facility layout of Jingdong Mine. The mine ventilation system 3D visualization model was established through VentAnaly. The paper determined the location and amount of regulation by using minimum power consumption interactive pathways regulating method. The total resistance reduced 550 Pa by field measurement after optimization. Air simulation error at wind site and main roadway is less than 5%, which met the actual demand.